Nowadays, assembling large eukaryotic genomes is more accessible than ever. This is in large part due to the fact that Oxford Nanopore Technologies (ONT) has made tremendous strides towards improving the throughput of their sequencers.
For example, Michael et al. recently described the ability to obtain highly-contiguous Arabidopsis thaliana assemblies from a single MinION flow-cell. It's also becoming clear that the PromethION is reaching insanely high levels of throughput, producing Terabases of data in just days.Continue reading